Title Number of addictive substances used related to increased risk of unnatural death: a combined medico-legal and case-record study.
Authors Louise Brådvik, Mats Berglund, Arne Frank, Anna Lindgren, Peter Löwenhielm
Alternative Location http://www.ncbi.nlm.nih.gov..., Restricted Access
Alternative Location http://dx.doi.org/10.1186/1..., Restricted Access
Publication BMC psychiatry
Year 2009
Volume 9
Issue Aug 4
Pages
Document type Article
Status Published
Quality controlled Yes
Language eng
Abstract English BACKGROUND: Substance use disorders have repeatedly been found to lead to premature death, i.e. drug-related death by disease, fatal intoxications, or trauma (accidents, suicide, undetermined suicide, and homicide). The present study examined the relationship between multi-drug substance use and natural and unnatural death. METHODS: All consecutive, autopsied patients who had been in contact with the Addiction Centre in Malmö University Hospital from 1993 to 1997 inclusive were investigated. Drug abuse was investigated blindly in the case records and related to the cause of death in 387 subjects. RESULTS: Every substance apart from alcohol used previously in life added to the risk of unnatural death in a linear way. There were independent increased risks of fatal heroin overdoses or undetermined suicide. Death by suicide and violent death were unrelated to additional abuse. CONCLUSION: The number of drugs used was related to an increased risk of unnatural death by undetermined suicide (mainly fatal intoxications) and heroin overdose.
ISBN/ISSN/Other ISSN: 1471-244X

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