Johan Lindström, Centre for Mathematical Sciences, Lund Title: Spatio-Temporal Modelling of local ambient air pollution. Abstract: The Multi-Ethnic Study of Atherosclerosis (MESA) Air is a major cohort study focused on the association between cardiovascular disease and chronic exposure to ambient air pollution. In order for MESA Air to estimate health effects we must first provide good predictions of ambient air pollution at subject locations. Here I will describe the modelling and prediction of NOx in Los Angeles and Baltimore. The main focus of the study is on chronic exposure (i.e. long term averages at each location). However, the long study period combined with the prohibitive cost of long term monitoring at many locations has lead to a very complex dataset; containing a mixture or long time series at a few locations, and spatially rich data at a few time points. The complex dataset has necessitated the development of a novel spatio-temporal model for air pollution. This talk will describe the available MESA Air NOx data in Los Angeles and Baltimore and the statistical methods developed to predict air pollution at subject locations. Finally I will also discuss our efforts to combine observations with the output from deterministic air pollution models in attempt to increase prediction accuracy.