Mats Kvarnström "Statistical tools in quantitative imaging" Abstract: Quantitative imaging is when one not only describes qualitatively what is observed in images, but instead measures various entities extracted from the images. Since the amount of images is typically huge, this is a very tedious task for humans. Therefore computer assistance is needed and statistical image analysis plays a vital role for the successful extraction of information. The need for competence in mathematical statistics in quantitative imaging for systems and cell biology, where the data often consists of large sets of images, is immense. I will here present two examples of quantitative imaging: positioning and tracking of sub-micrometer spherical particles, and cell recognition and the localization of proteins in cells. Both examples use images from wide-field microscopy (bright-field and fluorescence microscopy). Focus will be on various statitistical tools and challenges.